Search on: HTLV III GP120 
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Descriptor English:   HIV Envelope Protein gp120 
Descriptor Spanish:   Proteína gp120 de Envoltorio del VIH 
Descriptor Portuguese:   Proteína gp120 do Envelope de HIV 
Synonyms English:   HIV Envelope Glycoprotein gp120
gp120 Envelope Glycoprotein, HIV
HTLV III gp120
gp120, HTLV-III
Envelope Glycoprotein gp120, HIV
HTLV-III gp120
env Protein gp120, HIV
gp120(HIV)  
Tree Number:   D12.776.964.775.325.164.249
D12.776.964.775.562.500.500
D12.776.964.970.880.325.164.249
D23.050.327.520.350
Definition English:   External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV. 
See Related English:   Peptide T
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24717 
Unique Identifier:   D015699 

Occurrence in VHL:
 

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